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Contents: Drospirenone 3 mg, ethinylestradiol 30 mcg
Indication: Prevent pregnancy. May also prevent wt gain & other symptoms related to fluid retention eg, bloating & swelling; reduce acne & greasiness of the skin & hair; lower the risk of anemia; relieve menstrual pain.
Dosage: 1 tab daily starting on the 1st day of menstrual cycle for 21 days, followed by a 7-day tab-free interval.
Contraindications: Hypersensitivity. Patients w/ or history of thrombosis, embolism; heart attack or stroke, angina pectoris; blood clotting disturbance eg, protein C deficiency; migraine w/ focal neurological symptoms; pancreatitis; liver illness, impairment or tumor; cancer of the breast or sexual organs. Kidney failure; vag bleeding of unknown cause; diabetes w/ damaged blood vessels; very high BP & cholesterol or triglyceride levels in the blood. Pregnancy.
Special Precautions: Family history of breast cancer. Liver or gallbladder illness, diabetes, depression, Crohn's disease, ulcerative colitis, hemolytic uremic syndrome, sickle cell disease, epilepsy, SLE; hearing loss, porphyria, gestational herpes, Sydenham's chorea; chloasma, hereditary angioedema. Increased risk of developing arterial & venous thrombosis. May interfere w/ lab tests results. Lactation.
Adverse Reactions: Emotional lability, headache, abdominal pain, acne, sore & enlarged breasts, painful or irregular menstruation, wt gain.
Drug Interactions: Primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine; rifampicin; ritonavir; griseofulvin, ampicillin, tetracyclines; St. John's wort; ciclosporin. Increased seizure frequency w/ lamotrigine.
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